The modified checklist for autism in toddlers: a follow-up study investigating the early detection of autism spectrum disorders.

نویسندگان

  • Jamie M Kleinman
  • Diana L Robins
  • Pamela E Ventola
  • Juhi Pandey
  • Hilary C Boorstein
  • Emma L Esser
  • Leandra B Wilson
  • Michael A Rosenthal
  • Saasha Sutera
  • Alyssa D Verbalis
  • Marianne Barton
  • Sarah Hodgson
  • James Green
  • Thyde Dumont-Mathieu
  • Fred Volkmar
  • Katarzyna Chawarska
  • Ami Klin
  • Deborah Fein
چکیده

Autism spectrum disorders (ASD) often go undetected in toddlers. The Modified Checklist for Autism in Toddlers (M-CHAT) was used to screen 3,793 children aged 16-30 months from low- and high-risk sources; screen positive cases were diagnostically evaluated. Rescreening was performed on 1,416 children aged 42-54 months. Time 1 Positive Predictive Value (PPV) was .36 for the initial screening and .74 for the screening plus follow-up telephone interview; values were similar for Time2 PPV. When separating referral sources, PPV was low for the low-risk sample but acceptable with the followup telephone interview. Children with ASD from the low-risk and high-risk samples were highly similar. Results indicate that the M-CHAT continues to be a promising instrument for the early detection of ASD.

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عنوان ژورنال:
  • Journal of autism and developmental disorders

دوره 38 5  شماره 

صفحات  -

تاریخ انتشار 2008